Publisher Correction: Eggs sense high-fat diet

When is a high fat diet not a high fat diet?

The observation that a high fat/low carbohydrate (CHO) diet has a beneficial effect on a mouse model of Alzheimer's disease (AD) published today is notable given previous results showing that high fat diets have a deleterious effect on AD. Van de Auwera, et al. [1] reported that mice fed a ketogenic diet (<1% carbohydrate, 80% fat) were found to have a 25% decrease in the protein Aβ42 compared ...

Correction: Hepatocyte-Specific Depletion of UBXD8 Induces Periportal Steatosis in Mice Fed a High-Fat Diet

Correction: High Fat Diet Subverts Hepatocellular Iron Uptake Determining Dysmetabolic Iron Overload

Increased serum ferritin associated with mild hepatic iron accumulation, despite preserved upregulation of the iron hormone hepcidin, is frequently observed in patients with dysmetabolic overload syndrome (DIOS). Genetic factors and Western diet represent predisposing conditions, but the mechanisms favoring iron accumulation in DIOS are still unclear. Aims of this study were to assess the effec...

Correction: Dual Mode Action of Mangiferin in Mouse Liver under High Fat Diet

Chronic over-nutrition is a major contributor to the spread of obesity and its related metabolic disorders. Development of therapeutics has been slow compared to the speedy increase in occurrence of these metabolic disorders. We have identified a natural compound, mangiferin (MGF) (a predominant component of the plants of Anemarrhena asphodeloides and Mangifera indica), that can protect against...

High fat diet causes rebound weight gain.

Obesity is at epidemic proportions but treatment options remain limited. Treatment of obesity by calorie restriction (CR) despite having initial success often fails due to rebound weight gain. One possibility is that this reflects an increased body weight (BW) set-point. Indeed, high fat diets (HFD) reduce adult neurogenesis altering hypothalamic neuroarchitecture. However, it is uncertain if t...